Endocrine Abstracts

Background: Neurofibromatosis 1 (NF-1) is an autosomal-dominant multisystemic neurocutaneous disorder. It has long been appreciated that NF-1 is associated with endocrine conditions. The well reported endocrine conditions in NF-1 are growth hormone deficiency, central precocious puberty, pheochromocytoma and gastrointestinal neuroendocrine tumors including insulinoma. Furthermore, individuals with NF-1 are at increased risk of some malignancies including soft tissue sarcomas, ...

Background: Non-Diabetic Hypoglycemia is a rare entity in Endocrinology. After the confirmation of hypoglycemia with Whipple’s triad and excluding drug induced hypoglycemia, identification of underlying etiology using appropriate and targeted investigations is fundamental to institute specific management. It is challenging in resource poor settings due to unavailability and high cost of some investigations such as insulin autoantibodies and insulin-like growth factr-2 (IG...